Urethral cancer is a rare but serious medical condition that affects the urethra, a tube that carries urine from the bladder to the outside of the body. In this comprehensive article, we will delve deep into the causes, symptoms, and risk factors associated with urethral cancer. Our goal is to provide you with a thorough understanding of this condition to help you make informed decisions and take proactive steps when it comes to your health.


What Is Urethral Cancer?

Urethral cancer is a malignancy that originates in the cells of the urethra, the tube responsible for carrying urine from the bladder to the external body opening. This type of cancer is relatively rare, accounting for only a small percentage of all urological cancers. It primarily affects older individuals, with a higher incidence in women. Urethral cancer can be broadly categorized into two main types: squamous cell carcinoma and transitional cell carcinoma. The exact cause of urethral cancer is still under investigation, but several factors are believed to contribute to its development.


Causes of Urethral Cancer

The precise cause of urethral cancer remains elusive, but several risk factors and potential contributing elements have been identified. While it’s essential to remember that not everyone with these risk factors will develop urethral cancer, understanding them can aid in early detection and prevention:

  • Gender: Urethral cancer is more common in women than in men. The reasons behind this gender disparity are not yet fully understood, but it highlights the importance of regular screenings for women.
  • Age: Urethral cancer typically affects older individuals, with the highest incidence in people aged 60 and older. Regular check-ups and awareness become crucial as one ages.
  • Smoking: Smoking is a known risk factor for urethral cancer. Tobacco smoke contains carcinogens that can affect the cells lining the urethra.
  • Chronic Infections: Chronic infections, particularly sexually transmitted infections, such as human papillomavirus (HPV), can increase the risk of developing urethral cancer.
  • Chemical Exposures: Exposure to certain chemicals in the workplace or through environmental factors may play a role in the development of urethral cancer. Occupational exposure to substances like arsenic has been linked to an increased risk.
  • Radiation Exposure: Previous radiation therapy in the pelvic area for other medical conditions may elevate the risk of developing urethral cancer.


Symptoms of Urethral Cancer

Early detection is vital in the successful treatment of urethral cancer. Recognizing the signs and symptoms can help individuals seek medical attention promptly. Common symptoms of urethral cancer include:

  • Bloody Urine: Hematuria, or blood in the urine, is a frequent symptom of urethral cancer. If you notice any changes in the color of your urine, it’s essential to consult a healthcare professional.
  • Frequent Urination: An increased urge to urinate, along with discomfort or pain during urination, can be indicative of urethral cancer.
  • Pelvic Pain: Persistent pain in the pelvic area, lower abdomen, or back may signal a problem with the urethra.
  • Urinary Retention: Difficulty emptying the bladder, a feeling of incomplete emptying, or frequent urinary tract infections should be evaluated.
  • Mass or Lump: A visible mass or lump in the urethral area is a concerning sign and should be examined promptly.
  • Incontinence: Loss of bladder control or incontinence that is new or worsening should not be ignored.


Risk Factors for Urethral Cancer

Understanding the risk factors associated with urethral cancer can aid in its prevention and early detection. In addition to the causes mentioned earlier, some specific risk factors to be aware of include:

  • Genetic Predisposition: Individuals with a family history of urethral cancer may have a higher risk, emphasizing the importance of regular screenings.
  • Weakened Immune System: Conditions or medications that weaken the immune system can increase susceptibility to urethral cancer.
  • Chronic Inflammation: Chronic inflammation in the urethra, possibly due to recurrent infections, may contribute to the development of cancer.
  • Unprotected Sexual Activity: Engaging in unprotected sexual activity can expose individuals to sexually transmitted infections, which are associated with a higher risk of urethral cancer.
  • Obesity: Being overweight or obese is linked to an increased risk of several types of cancer, including urethral cancer.



Urethral cancer is a rare but serious condition that primarily affects older individuals and is more common in women. While the exact cause remains uncertain, various risk factors, such as smoking, chronic infections, and chemical exposures, have been identified. Recognizing the symptoms, such as bloody urine and pelvic pain, is crucial for early detection.

Understanding the risk factors, including genetic predisposition and a weakened immune system, can aid in preventing urethral cancer. By staying informed and proactive, individuals can take steps to protect their health and seek medical attention when needed. Early detection and treatment can significantly improve outcomes for those affected by urethral cancer.

Desert Sky Urology

If you or a loved one is in need of urethral cancer treatment, it’s crucial to seek the expertise of the best urologist in Arizona. Look no further than Desert Sky Urology.


At Desert Sky Urology, we are committed to providing the highest quality of care to our patients. Dr. Byrne is a top urologist in Arizona.

Don’t delay in getting the treatment you need. Contact Desert Sky Urology today to schedule an appointment. Your health and well-being are our top priorities, and we are here to guide you through your urethral cancer treatment journey.